Nutraceuticals Division
DESCRIPTION:
Non-Pareil Seeds are spherical particles of uniform diameter. They are white, uniform granules that are practically inert, tasteless and odorless. Non-Pareil seeds are primarily composed of inert substances like starch. Non-Pareil seeds are usually white in colour but can also be made in a variety of colours based on specification. Non-Pareil seeds are stable at ambient conditions.
APPLICATIONS:
Non-Pareil Seeds are generally used as cores in sustained release formulations. Here, the Non- Pareil Seeds is the base upon which drugs are coated. The Non—Pareil seeds are then given a protective barrier. As sustained release formulations usually contain more than one dose of a given drug, the use of Non-Pareil Seeds will offer several advantages over other mechanisms:
(1) Subdividing the multiple doses onto many seeds, the risk of barrier failure and ‘Dose dumping’ of the drug can be reduced.
(2) When more than one drug is used in a formulation, Non-Pareil Seeds offer the advantage of using different barriers for different drugs in the same dosage form. In order to formulate for these characteristics, each drug is coated onto separate batches of Non-Pareil Seeds and given different protective barriers. This approach permits more than one drug to be incorporated into the dosage form while individually adjusting the mechanism to achieve the desired release profile for each drug individually.
3) By coating each drug onto Non-Pareil Seeds separately, the assays for each can be carried out separately without interference from the other drugs. If any batch of drug is found to be deficient, it can be adjusted/ discarded without the loss of other drugs in the formulation.
(4) Drug-coated Non-Pareil Seeds can be given coatings of inert colors that distinguish one drug from another. These can be blended and filled into capsule shells or incorporated in a suitable directly compressible vehicle and compressed into tablets.
(5) As different mechanisms for each drug delivery may produce barrier coatings of different thickness, a range Non-Pareil Seeds of different sizes can be made available.
PACKAGING:
Non-Pareil Seeds are available in polyethylene-lined drums.
SUGAR PELLETS:
Sugar Pellets are neutral pellets made of sucrose and starch.
The almost spherical cores are used as nutral basis for drug layering.
| Mesh Size (ASTM) | Diameter in mm |
| SS 30 – 40# | 0.595 – 0.420 |
| SS 25 – 30# | 0.707 – 0.595 |
| SS 20 – 25# | 0.841 – 0.707 |
| SS 18 – 20# | 1.00 – 0.841 |
| SS 16 – 20# | 1.19 – 0.841 |
| SS 16 – 18# | 1.19 – 1.00 |
| SS 14 – 16# | 1.41 – 1.19 |
| SS 12 – 14# | 1.68 – 1.41 |
STARCH PELLETS:
Used as spherical seed cores for drug layering and film coating.
Also used in manufacture of granules/beadlets with sustained/controlled release, taste masking and other special properties.
| Mesh Size (ASTM) | Diameter in mm |
| SS 30 – 40# | 0.595 – 0.420 |
| SS 25 – 30# | 0.707 – 0.595 |
| SS 20 – 25# | 0.841 – 0.707 |
| SS 18 – 20# | 1.00 – 0.841 |
| SS 16 – 20# | 1.19 – 0.841 |
| SS 16 – 18# | 1.19 – 1.00 |
| SS 14 – 16# | 1.41 – 1.19 |
| SS 12 – 14# | 1.68 – 1.41 |
MANUFACTURING FACILITY:
Manufacturing facility of Unijules Life Sciences Ltd. is designed as per latest GMP Guidelines.
Our production area is maintained with ISO Class 8 with temperature and humidity control.
Our quality control is equipped with microbiology testing and equipment like HPLC and camsizer for precise testing.
Our QA/IPQA Team ensures the well controlled manufacturing process and working as per predefined SOPs.
APPROVALS:
1. WHO GMP
2. BRC ISSUE 8
3. HACCP
4. SA8000
5. ISO 22000
6. ISO 9001:2015
7. HALAL
FACILITIES:
CERTIFICATIONS:
